The Sutra of Bhaisajyaguru serves as the primary scripture for the Bhaisajyaguru faith. In the history of 
sutra translation in China, it has been translated into Chinese five times. With the exception of the Liu Song Dynasty translation, the other four versions are preserved in Taishō Tripiṭaka. However, only Bhaisajyaguru-Vaidūrya-Prabhāsa-Saptabuddha-Pūrva-Pranidhana-Sūtra, translated by Yijing of the Tang Dynasty, was transmitted to Tangut. Tangut monks translated Yijing’s Chinese version into Tangut, with some copies preserved in Tangut texts unearthed at Khara-Khoto and Dunhuang. This paper primarily examines the Tangut version of Bhaisajyaguru-Vaidūrya-Prabhāsa-Saptabuddha-Pūrva-Pranidhana-Sūtra unearthed at Khara-Khoto, along with its ritual practices. Specifically, by translating and interpreting Tangut scripture fragments from Khara-Khoto held in British collections, this paper determines the number of extant pages and corrects erroneous indentifications. Subsequently, it investigates the date of the Tangut translation of the sutra and the Tangut monk Dehui’s honorary title as well as his compilation of Homa Ritual for the Bhaisajyaguru-Vaidūrya- Prabhāsa-Saptabuddha, and finally examines various influencing factors of the circulation of the sutra within Tangut.